Mitosis and Cytokinesis

Rucete ✏ Biology In a Nutshell

1. What Is Mitosis?

  • Mitosis is the process in which the nucleus of a eukaryotic cell divides, producing two genetically identical daughter nuclei.
  • It ensures equal distribution of chromosomes.

2. Phases of Mitosis

Prophase

  • The nucleolus disappears.
  • Chromatin condenses into sister chromatids.
  • The mitotic spindle begins to form in the cytoplasm.
  • Microtubules extend from MTOCs (microtubule-organizing centers).
  • The nuclear envelope breaks down.
  • Microtubules attach to kinetochores of chromatids.

Metaphase

  • Sister chromatids align at the metaphase plate (center of the cell).
  • This alignment ensures equal division.

Anaphase

  • Sister chromatids separate, becoming individual chromosomes.
  • Chromosomes are pulled to opposite poles by the spindle apparatus.

Telophase

  • New nuclear envelopes form around the separated chromosomes.
  • Nucleoli reappear, and chromosomes decondense.

3. What Is Cytokinesis?

  • Cytokinesis is the process of dividing the cytoplasm to form two separate daughter cells, following mitosis.

4. Cytokinesis in Plant Cells

  • Golgi vesicles accumulate between the two forming nuclei.
  • Vesicles fuse to form a cell plate.
  • The cell plate develops into new plasma membranes and a cell wall.

5. Cytokinesis in Animal Cells

  • Microfilaments form a contractile ring around the center of the cell.
  • The ring contracts, forming a cleavage furrow that pinches the cell into two.

6. Interphase

  • The phase before mitosis, where the cell grows and replicates its DNA.
  • Subphases: G₁ → S → G₂

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