Meiosis

Rucete ✏ Biology In a Nutshell

1. What Is Meiosis?

  • Meiosis is a type of cell division that reduces the chromosome number by half, producing four haploid cells (n) from one diploid cell (2n).
  • It occurs in germ cells and is essential for sexual reproduction.

2. Overview

  • Meiosis consists of two divisions:
    • Meiosis I: separates homologous chromosomes
    • Meiosis II: separates sister chromatids
  • Results in four genetically unique haploid cells.

3. Meiosis I: Reduction Division

Prophase I

  • Homologous chromosomes pair up (synapsis) and form tetrads.
  • Crossing over occurs—exchange of genetic material between homologs.

Metaphase I

  • Tetrads align at the metaphase plate.
  • Orientation is random → contributes to genetic variation.

Anaphase I

  • Homologous chromosomes separate and move toward opposite poles.
  • Sister chromatids remain attached.

Telophase I

  • Homologous pairs finish moving to opposite poles.
  • Nuclear envelope may reform in some species.

Cytokinesis I

  • Two haploid cells are formed, each with duplicated chromosomes.

4. Meiosis II: Division of Sister Chromatids

Prophase II

  • New spindle forms in each haploid cell.
  • Nuclear envelope breaks down (if it had reformed).

Metaphase II

  • Chromosomes align at the center (metaphase plate).

Anaphase II

  • Sister chromatids separate and move to opposite poles.

Telophase II

  • Nuclei reform around the chromosomes.
  • Chromosomes decondense.

Cytokinesis II

  • Four genetically distinct haploid daughter cells are produced.

In a nutshell

  • Produces 4 non-identical haploid cells.
  • Ensures genetic diversity via:
    • Crossing over (Prophase I)
    • Independent assortment (Metaphase I)

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