Genetic Equilibrium

Rucete ✏ Biology In a Nutshell

1. What Is Genetic Equilibrium?

Genetic equilibrium refers to a condition where allele frequencies in a population remain constant over generations, assuming certain conditions are met.
This is described by the Hardy-Weinberg principle.

2. Hardy-Weinberg Conditions

For a population to remain in genetic equilibrium, the following five conditions must be met:

  1. No mutation
  2. No gene flow (no migration in or out)
  3. No genetic drift (large population size)
  4. No natural selection
  5. Random mating

3. Hardy-Weinberg Equations

a) Allele Frequency Equation

p + q = 1

  • p = frequency of the dominant allele
  • q = frequency of the recessive allele

b) Genotype Frequency Equation

p² + 2pq + q² = 1

  • = frequency of homozygous dominant (AA)
  • 2pq = frequency of heterozygous (Aa)
  • = frequency of homozygous recessive (aa)

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