The Endocrine System

Rucete ✏ Biology In a Nutshell

1. Hypothalamus

  • Produces ADH and oxytocin, stored and secreted by the posterior pituitary
  • Acts as a major neuroendocrine center

2. Posterior Pituitary (Stores & Releases)

  • ADH (Antidiuretic Hormone) → kidneys: increases water reabsorption
  • Oxytocin → mammary glands: stimulates milk release

3. Anterior Pituitary (Produces Hormones)

  • TSH (Thyroid-Stimulating Hormone) → thyroid: secretion of T3 and T4
  • ACTH (Adrenocorticotropic Hormone) → adrenal cortex: secretion of glucocorticoids
  • FSH (Follicle-Stimulating Hormone) → ovaries/testes: oogenesis and spermatogenesis
  • LH (Luteinizing Hormone) → ovaries/testes: ovulation and testosterone production
  • PRL (Prolactin) → mammary glands: milk production
  • GH (Growth Hormone) → bones, muscles: stimulates growth

4. Pancreas (Islets of Langerhans)

  • Alpha cells: secrete glucagon → liver: increases blood glucose
  • Beta cells: secrete insulin → liver, muscles, fat: lowers blood glucose

5. Adrenal Glands

a) Adrenal Medulla

  • Epinephrine (adrenaline) and norepinephrine (noradrenaline)
  • Target: blood vessels, liver, heart
  • Action: increases blood glucose, constricts vessels

b) Adrenal Cortex

  • Glucocorticoids → general: increases blood glucose
  • Mineralocorticoids → kidneys: increases Na⁺ reabsorption, K⁺ excretion

6. Thyroid Gland

  • T4 (thyroxine) and T3 (triiodothyronine) → general: increases metabolic rate
  • Calcitonin → bones: lowers blood Ca²⁺

7. Parathyroid Glands

  • PTH (Parathyroid Hormone) → bones: increases blood Ca²⁺

8. Testes

  • Testosterone → testes, general: promotes spermatogenesis and secondary sex characteristics

9. Ovaries

  • Estrogen → uterus: regulates menstrual cycle, secondary sex characteristics
  • Progesterone → uterus: regulates menstrual cycle and supports pregnancy

10. Pineal Gland

  • Melatonin → body: regulates circadian rhythms

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