Hormonal Control of Human Reproduction

Rucete ✏ Biology In a Nutshell

1. Menstrual Cycle Overview

  • A recurring cycle (~28 days) involving the thickening and shedding of the endometrium in preparation for potential implantation.

2. Key Hormonal Events

a) Hypothalamus

  • Releases GnRH (Gonadotropin-releasing hormone)

b) Anterior Pituitary

  • Releases FSH (Follicle-Stimulating Hormone) and LH (Luteinizing Hormone) in response to GnRH
  • FSH stimulates development of the follicle and maturation of the oocyte
  • LH triggers ovulation and the formation of the corpus luteum

3. Ovarian Cycle Phases

a) Follicular Phase (Days 1–13)

  • FSH promotes follicle growth
  • Maturing follicle secretes estrogen, which thickens the endometrium

b) Ovulation (Day 14)

  • A surge in LH triggers the release of the secondary oocyte from the ovary

c) Luteal Phase (Days 15–28)

  • Corpus luteum forms and secretes estrogen and progesterone
  • These hormones maintain the thickened endometrium
  • If no fertilization, the corpus luteum degenerates, hormone levels drop, and menstruation occurs

4. Hormonal Feedback and Pregnancy

  • If fertilization occurs, the implanted embryo releases hCG (Human Chorionic Gonadotropin)
  • hCG maintains the corpus luteum, allowing continued production of estrogen and progesterone
  • This prevents menstruation and supports early pregnancy

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